Scientist > Dr Frank Steiner

Dr Frank Steiner

// graduated in chemistry before obtaining his doctorate in 1995 from Saarland University in Saarbrücken

// This was followed by a postdoc position at the Centre d'Études Nucléaires de Saclay in France, where he worked on elemental analysis and isotope analysis with IC and IC-ICP/MS

// He then returned to Saarland University, where he completed his habilitation in 2003

// After a two-year period of research and teaching, he accepted in 2005 a position as LC Systems Manager at Dionex Softron GmbH, a part of Thermo Fisher Scientific

Contact: laborundmore@succidia.de

Does increased LC peak capacity equal increased value for complex sample analysis?

The meaning of peak capacity - von Dr Frank Steiner

Despite the strength of liquid chromatography (LC) to separate compounds through well tunable selective retention, its efficiency lags behind gas chromatography (GC) that can deliver up to several millions of plates per column. Resolution improvement in LC should thus be addressed with selectivity optimization first. If samples get too complex, however, this approach is no longer feasible, as improving selectivity in one part of the chromatogram will...

Pharmaceutical counterion determination

House lights down, stage lights up - von Dr Frank Steiner, Dr Carsten Paul, Dr Mark Tracy

In contemporary practice, roughly half of all active pharmaceutical ingredients (APIs) are administered as salts. The use of the protonated or deprotonated form of the drug substance combined with the selection of counterions enables the targeted variation of key parameters, such as solubility and stability. Analysis of the corresponding counterions constitutes an essential part of the development process for new pharmaceuticals and is now an...